Studies of gene regulation and cell metabolism have typically focused on one process or the other, and yet these processes are mostly intertwined. Metabolism is driven by specific enzymatic products of gene expression. In turn, gene expression requires

Growth factor-stimulated or cancerous cells require sufficient nutrients to meet the metabolic demands of cell growth and division. If nutrients are insufficient, metabolic checkpoints are triggered that lead to cell cycle arrest and the activation

“Tell me what you eat and I will tell you what you are” Jean Anthelme Brillat-Savarin, 1826 The internet and magazines are filled with a dazzling array of metabolic intermediates and byproducts whose consumption would appear to cure all that ills us,