Immortalized cell lines derived from dental/odontogenic tissue
WebApr 11, 2023 · An immortalized mouse floxed Bmp2 dental papilla mesenchymal cell line (iBmp2-dp cells) was generated for studying the mechanisms of stem cells from dental/odontogenic tissue differentiation and dentin formation mediated by Bmp2 (Wu et al. 2010 ). Furthermore, Cre fluorescent protein (GFP) was inducted into iBmp2-dp cells to …
Pulp (tooth) - Wikipedia
WebCells found in the dental pulp include fibroblasts (the principal cell), odontoblasts, defence cells like histiocytes, macrophages, granulocytes, mast cells, and plasma cells. The nerve plexus of Raschkow is located central to the cell-rich zone. The plexus of Raschkow. The plexus of Raschkow monitors painful sensations. By virtue of their peptide content, they …
Clinical Potential of Dental Pulp Stem Cells in Pulp Regeneration ...
WebApr 11, 2022 · Dental pulp cells proliferate when periodontal tissue is damaged, migrate to the damaged site, then differentiate into odontoblasts to form reparative dentin (Tziafas et al., ... Frozoni M., Zaia A. A., Line S. R. P., Mina M. (2012). Analysis of the Contribution of Nonresident Progenitor Cells and Hematopoietic Cells to Reparative Dentinogenesis …
The roles of odontoblasts in dental pulp innate immunity
WebMar 27, 2018 · In contrast, human dental pulp cells (HDPCs) showed a low level of NOD2 protein expression . Another study reported that significant up-regulation of NOD2 gene as well as tumor necrosis factor (TNF)-α occurs in acute inflamed human dental pulps compared to healthy ones. ... IL-8, and TNF-α in a rat odontoblast-like cell line via the …
Effects of Hyaluronic Acid Sponge as a Scaffold on Odontoblastic Cell …
WebJan 1, 2010 · Based on the abundant CDots-induced ECM and thereby the reinforcement of the cell-ECM adhesion, an intact dental pulp stem cell sheet can be achieved, which in return promote in vivo the efficient ...
Dental Pulp Fibroblast: A Star Cell - PubMed
WebAbstract. Introduction: Dental pulp fibroblasts (DPFs) are the most abundant cell type in the dental pulp. They play pivotal roles; however, they are often mistaken to be involved only in the repair and maintenance of this connective tissue. Methods: We used the search terms "pulp fibroblast," "complement system proteins," "pulp inflammation ...
Establishment of Stable Cell Lines from Primary Human Dental Pulp …
WebThis protocol is for the isolation of primary human dental pulp stem cells (DPSCs) from adult extracted molars, and for the generation of high titer lentivirus for in vitro infection of the DPSCs. Stable cell lines of dental pulp stem cells are generated, maintained in culture, and used for subsequent experiments.
Human dental pulp stem cells: Applications in future regenerative ...
WebJun 6, 2015 · INTRODUCTION. Stem cells are unspecialized cells having a property of self renewal and further differentiate into various types of specialized cells[].Stem Cells are identified in a number of adult tissues including skin, adipose tissues[], peripheral blood[3,4], bone marrow, pancreas, intestine, brain, hair follicles, as well as in the dental pulp …
Dental Pulp Stem Cells: Advances to Applications - PubMed
WebFeb 13, 2020 · Dental pulp stem cells (DPSCs) have a high capacity for differentiation and the ability to regenerate a dentin/pulp-like complex. Numerous studies have provided evidence of DPSCs' differentiation capacity, such as in neurogenesis, adipogenesis, osteogenesis, chondrogenesis, angiogenesis, and dentinogenesis. The molecular …
Dentin-pulp complex development – Histology and Embryology for Dental ...
WebThe lines that should be clearly visible in the layer of dentin in Fig. 10.6 are dentinal tubules, ... A cell of neural crest origin that is part of the outer surface of the dental pulp, and whose biological function is the formation of dentin. ... Dentin produced by the differentiation of pulp stem cells becoming later odontoblast and/or osteoblast-like cells, which form a bone …
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