Cellular Metabolism at a Glance - PubMed
वेबMetabolism is highly coordinated component of the cellular activity that involves sequential chemical transformations, within a so-called metabolic network. Through these coordinated actions, living organisms acquire energy and biosynthetic precursors to maintain cellular homeostasis and function. Metabolism relies on the breaking down of ...
Acetate controls endothelial-to-mesenchymal …
वेब15 जून 2023 · Endothelial-to-mesenchymal transition (EndMT) is initiated by activation of endothelial TGF-β signaling. Induction of EndMT results in increased ACSS2-dependent Ac-CoA synthesis from pyruvate-derived …
Metabolism - PMC - National Center for Biotechnology Information
वेब24 अग॰ 2020 · Metabolism is derived from the Greek word, metabolē meaning ‘to change’ and comprises the total of all chemical reactions that take place in the cell that are essential for life. These chemical reactions comprise both the synthesis and degradation of complex macromolecules and can be divided into either catabolism or anabolism ( Figure 1 – …
The Power of Plasticity—Metabolic Regulation of Hepatic ... - Cell …
वेबHepatic stellate cells (HSCs) are resident non-parenchymal liver pericytes whose plasticity enables them to regulate a remarkable range of physiologic and pathologic responses. To support their functions in health and disease, HSCs engage pathways regulating carbohydrate, mitochondrial, lipid, and retinoid homeostasis. In chronic liver injury, HSCs …
Deciphering the metabolic heterogeneity of hematopoietic stem cells …
वेब2 जन॰ 2024 · The predicted metabolites covered glycolysis, citrate cycle, pentose phosphate pathway (PPP), pyruvate metabolism, amino acid biosynthesis, pyrimidine metabolism, etc. t-SNE visualization of metabolomics differences between stem and progenitor cell populations by SVM analysis showed that all hematopoietic cell (sub)populations could …
Dietary fructose-mediated adipocyte metabolism drives ... - Cell …
वेब19 अक्तू॰ 2023 · The impact of dietary fructose on antitumor immunity remains unclear. Zhang et al. reveal that dietary fructose initiates leptin production in adipocytes in an mTORC1-dependent manner and mediates leptin-boosted antitumor functions of CD8+ T cells, suggesting that the fructose-leptin axis may be harnessed for immunotherapy …
Metabolism in Pluripotent Stem Cells and Early Mammalian …
वेबThe importance of cell metabolism is straightforward in certain contexts, such as building biomass for cell proliferation, compared with less obvious contexts, such as during cell-state transitions driven by epigenetic remodeling and specific gene activation or suppression. There is rapidly accumulating evidence for extensive, interdependent interactions …
Cell Metabolism - Scimago Journal & Country Rank
वेबEstablished in 2005, Cell Metabolism is the top research journal dedicated to publishing novel, impactful papers spanning basic to clinical metabolic research. We are interested in original research addressing the molecular mechanisms underlying physiological homeostasis and what goes awry in disease. The journal's mission is to provide the ...
Introduction to metabolism: Anabolism and catabolism
वेब25 अग॰ 2015 · Metabolism refers to the set of chemical reactions that occur within living organisms to maintain life. Anabolism is the process of building up larger, more complex molecules from smaller ones. …
- लेखक: Sal Khan
Beggars banquet: Metabolism in the tumor immune ... - Cell Press
वेब29 जून 2023 · Metabolism, the nervous system, and the immune system form a triumvirate of homeostasis. Recent research is exploring roles of this triumvirate in the TME. Neurotransmitters such as norepinephrine, aminobutyric acid (GABA), and acetylcholine have been studied in the context of tumor immunity and immunotherapy.
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