JOURNAL OF CELL BIOLOGY_影响因子(IF)_中科院分区_SCI期刊投 …
ਵੈਬ23 ਮਾਰਚ 2024 · Journal of Cell Biology (JCB) is a broad journal that publishes original findings on all aspects of cell biology. We consider papers reporting new cellular or molecular advances in any areas of basic cell biology as well as papers that describe applied cell biology in a variety of systems including, but not limited to, immunology, …
USP9X-mediated REV1 deubiquitination promotes lung cancer ...
ਵੈਬ5 ਦਿਨ ਪਹਿਲਾਂ · REV1 is thought to be an important signaling node linking nutrient sensing and metabolic control to cell fate, and altered cellular metabolism is one of the hallmarks of tumorigenesis [30,31,32]. Sander Kooijman et al. found that REV1 deficiency leads to increased oxidative stress and mitochondrial dysfunction due to rapid NAD + …
Fluoride impairs vascular smooth muscle A7R5 cell lines via …
ਵੈਬ1 ਦਿਨ ਪਹਿਲਾਂ · These findings underscore the intricate mechanisms through which fluoride can disrupt cellular metabolism and function. In this study, a majority of the KEGG enrichment pathways are closely associated with amino acids metabolism. Pathways such as arginine and proline metabolism, glycine, serine, and threonine metabolism, alanine, …
Bacteria | Cell, Evolution, & Classification | Britannica
ਵੈਬ4 ਦਿਨ ਪਹਿਲਾਂ · bacteria, any of a group of microscopic single-celled organisms that live in enormous numbers in almost every environment on Earth, from deep-sea vents to deep below Earth’s surface to the digestive tracts of humans. Bacteria lack a membrane-bound nucleus and other internal structures and are therefore ranked among the unicellular life …
Sequential drug treatment targeting cell cycle and cell fate …
ਵੈਬ2 ਦਿਨ ਪਹਿਲਾਂ · Background Targeted therapies exploiting vulnerabilities of cancer cells hold promise for improving patient outcome and reducing side-effects of chemotherapy. However, efficacy of precision therapies is limited in part because of tumor cell heterogeneity. A better mechanistic understanding of how drug effect is linked to cancer …
Enhancing prime editing in hematopoietic stem and progenitor cells …
ਵੈਬ5 ਦਿਨ ਪਹਿਲਾਂ · Modulating nucleotide metabolism is a straightforward and effective approach to ameliorate prime editing in therapeutically relevant cell types, including primary cells (in which the cellular ...
《METABOLISM-CLINICAL AND EXPERIMENTAL》 - 爱科学
ਵੈਬ3 ਦਿਨ ਪਹਿਲਾਂ · Metabolism promotes excellence in research by publishing high-quality original research papers, fast-tracking cutting-edge papers, research brief reports, mini-reviews, and other special articles related to all aspects of human metabolism. Work considered for publication in Metabolism includes studies in humans, animal and …
New articles: Cell Systems
ਵੈਬ5 ਦਿਨ ਪਹਿਲਾਂ · Alexander R.A. Anderson. First published: May 20, 2024. Adaptive therapy tailors treatment to the tumor dynamics and could allow better matching of drug levels to the characteristics of a patient’s disease. Integrating real-time microscopy and mathematical modeling, we find that during PARPi maintenance in ovarian cancer, …