Controlled cell proliferation and immortalization of human dental pulp ...
വെബ്4 ദിവസം മുമ്പ് · We have engineered a novel human dental pulp stem cell line, distinguished by the constitutive expression of telomerase reverse transcriptase (TERT), and the conditional expression of the R24C mutant cyclin-dependent kinase 4 (CDK4 R24C) and Cyclin D1 (hereafter referred to as Tet-off K4DT). In Tet-off …
The profile of cytokines against bacterial infection in dental pulp
വെബ്3 ദിവസം മുമ്പ് · For the three populations of pulp stem cells with stem cell activity in the dental pulp, the secretion of cytokines related to nervous system development, regulation of endothelial cell proliferation and migration, and regulation of immune cell function comprised the characteristics that we observed. The …
The various forms of tooth resorption - Wiley Online Library
വെബ്5 ദിവസം മുമ്പ് · A resorption cavity forms containing clastic cells that line the periphery and progressively resorb the canal walls in a relatively symmetrical expansion ... If the infection advances and the entire pulp becomes necrotic, the clastic cells are cut off from the blood circulation and the process of internal …
Paracrine- and cell-contact-mediated immunomodulatory effects …
വെബ്1 ദിവസം മുമ്പ് · Mesenchymal stromal cells (MSCs) reside in the perivascular area [1, 2] of various tissues throughout the human body, including the bone marrow, umbilical cord, and adipose tissue [3, 4].Additionally, they can also be isolated from various dental tissues, such as the periodontal ligament (PDL) [], …
Extracellular vesicles from dental pulp mesenchymal stem cells …
വെബ്4 ദിവസം മുമ്പ് · Extracellular vesicles (EVs) derived from dental pulp mesenchymal stem cells (DP-MSCs) are a promising therapeutic option for the treatment of myocardial ischemia. The aim of this study is to determine whether MSC-EVs could promote a pro-resolving environment in the heart by modulating …
Bioprinting salivary gland models and their regenerative ... - Nature
വെബ്2 ദിവസം മുമ്പ് · Dental literature has reported the functional significance of hDPSC-derived EV, indicating their ability to activate dental pulp tissue regeneration, induce stem cell differentiation , and promote ...
Preventive Effects of Dental Pulp Stem Cell-conditioned
വെബ്3 ദിവസം മുമ്പ് · Medication-related osteonecrosis of the jaw is a serious disease occurring in patients with cancer and osteoporosis, who are undergoing treatment with antiresorptive agents (ARAs) such as bisphosphonate (BP) or denosumab, an antibody targeting receptor activator of NF-κB ligand. Recently, …
Comparative effects of 17% ethylenediaminetetraacetic acid and …
വെബ്5 ദിവസം മുമ്പ് · Background Growth factors embedded in the extracellular matrix of the dentin play an important role in the migration, proliferation, and differentiation of dental pulp stem cells in regenerative endodontics. In regenerative endodontic treatments, the type of irrigation solution used is crucial for the release …
Endodontic treatment of chronic apical periodontitis ameliorates ...
വെബ്3 ദിവസം മുമ്പ് · Twenty-seven consecutive Caucasian, dentate subjects between 14 and 55 years old, of normal weight and with no medical history of diabetes, systemic, oncologic or immune system diseases, who were referred to the Endodontic Department of a dental hospital in Northen Italy with a diagnosis of …
Biological differences between adult and perinatal human …
വെബ്2 ദിവസം മുമ്പ് · The biological properties of human mesenchymal stromal cells (hMSCs) have been explored in over a thousand clinical trials in the last decade. Although hMSCs can be isolated from multiple sources, the degree of biological similarity between cell populations from these sources remains to be determined. A …
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