Frontiers | The Regenerative Potential of bFGF in Dental Pulp …
ವೆಬ್ಜುಲೈ 19, 2021 · Histological and radiological results showed that the application of the nano-HAP/bFGF induced the invasion of dental pulp cells and vessels, indicating the regeneration of pulp tissue, and stimulated the formation of a dentinal bridge containing numerous dentinal tubules (Imura et al., 2019).
The Regenerative Potential of bFGF in Dental Pulp Repair and ...
ವೆಬ್ಜುಲೈ 20, 2021 · Histological and radiological results showed that the application of the nano-HAP/bFGF induced the invasion of dental pulp cells and vessels, indicating the regeneration of pulp tissue, and stimulated the formation of a dentinal bridge containing numerous dentinal tubules (Imura et al., 2019).
Hypoxia response element-directed expression of bFGF in dental pulp ...
ವೆಬ್ಆಗ 1, 2021 · Human dental pulp stem cells (DPSCs) are abundant stem cells with low immune rejection, which can be considered for cell replacement therapy. The purpose of this study was to investigate the roles of DPSCs which express bFGF under the regulation of five hypoxia-responsive elements (5HRE) using an adeno-associated virus (AAV …
Clinical Potential of Dental Pulp Stem Cells in Pulp Regeneration ...
ವೆಬ್ಏಪ್ರಿ 11, 2022 · Dental pulp stem cells (DPSCs) isolated from pulp tissue exhibit mesenchymal stem cell-like characteristics and are considered ideal candidates for regenerating damaged dental pulp tissue owing to their multipotency, high proliferation rate, and viability after cryopreservation.
Effect of Bioactive Glasses and Basic Fibroblast Growth Factor on ...
ವೆಬ್ಡಿಸೆಂ 18, 2023 · Treated dental pulp cells secrete neurotrophins and promote prominent neurite outgrowth toward the site of carious injury [43,44,45]. This study suggests that the BG + FGF-treated dental pulp cells positively regulate the growth and differentiation of glia in the dental pulp.
The possible role of basic fibroblast growth factor in dental pulp
ವೆಬ್ಜನವರಿ 1, 2020 · bFGF promotes dental pulp cell proliferation rather than differentiation. •. The effect of bFGF on differentiation depends on dose, duration, and cellular phase at exposure. •. bFGF appears to promote pulp regeneration in vivo. Abstract.
Basic Fibroblast Growth Factor Regulates Gene and Protein ... - PubMed
ವೆಬ್bFGF may be involved in pulpal repair and regeneration by activation of FGFRs to regulate cell growth; stimulate cdc2, cyclin B1, and TIMP-1 expression; and inhibit ALP. These events are partly associated with MEK/ERK signaling.
The possible role of basic fibroblast growth factor in dental pulp
ವೆಬ್ಜನವರಿ 1, 2020 · This review gives a comprehensive summary of the potential role of bFGF in dental pulp wound healing and regeneration in connection with cell proliferation and differentiation, angiogenesis, and neural differentiation.
Administration of Epidermal Growth Factor (EGF) and Basic
ವೆಬ್ಜನವರಿ 18, 2023 · This may include dental pulp stem cells (DPSCs), which have recently been demonstrated to produce neuronal precursors. Based upon this evidence, the primary aim of this study was to determine if the growth factors used in MSC-based studies are sufficient to induce neuronal differentiation among DPSCs.
Dental Pulp Stem Cells: Advances to Applications - PMC
ವೆಬ್ಫೆಬ್ರವರಿ 13, 2020 · Basic Fibroblast Growth Factor (bFGF) According to the literature, bFGF has been detected in DPSCs and after the endodontic procedure of irrigation. Basic FGF receptors (FGFR1 and FGFR2) were also found to be expressed in human dental pulp cells.
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